DPP4

DPP4, dipeptidyl peptidase 4, alias DPP-4 inhibitor. It is a cell-surface serine protease that is expressed mainly in the intestine, but also in the liver, pancreas, placenta, and thymus.The mechanism of action of DPP4 is mainly to inactivate a variety of biologically active peptides, including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic secretory polypeptide (GIP), which are target proteins of DPP-4 and can be DPP-4 Rapid degradation and inactivation by DPP-4 .

The biological significance of DPP4 is mainly reflected in its involvement in the regulation of blood glucose levels.DPP-4 inhibitors enhance insulin secretion and lower blood glucose by inhibiting the activity of DPP-4 and decreasing the degradation of GLP-1 and GIP.DPP-4 inhibitors have glucose-dependent glucose-lowering effects, low risk of hypoglycemia, and are associated with weight loss, Improvement of pancreatic β-cell function and other additional benefits . In addition, DPP-4 may play a key role in obesity-induced inflammation and insulin resistance, and the use of DPP-4 inhibitors may reduce obesity-induced inflammation and insulin resistance.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The purity of DPP4 was greater than 95% as determined by SEC-HPLC

DPP4 Recombinant Monoclonal Antibody (CSB-RA927191A0HU)

Validated Data

IHC image of CSB-RA927191A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

The following DPP4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

DPP4 Antibodies

DPP4 Proteins

DPP4 ELISA Kits

DPP4 Antibodies

DPP4 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA007139GA01HU	DPP4 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA830019	DPP4 Antibody	Human	WB, IHC, ELISA
CSB-PA06229A0Rb	DPP4 Antibody	Human, Rat	ELISA, WB, IHC, IF
CSB-PA06229B0Rb	DPP4 Antibody, HRP conjugated	Human	ELISA
CSB-PA06229C0Rb	DPP4 Antibody, FITC conjugated	Human
CSB-PA06229D0Rb	DPP4 Antibody, Biotin conjugated	Human	ELISA
CSB-RA927191A0HU	DPP4 Recombinant Monoclonal Antibody	Human	ELISA, IHC

DPP4 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA007139ZA01RA	Dpp4 Antibody	Rattus norvegicus	ELISA, WB (ensure identification of antigen)

DPP4 Proteins

DPP4 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP007139RA	Recombinant Rat Dipeptidyl peptidase 4 (Dpp4), partial,Yeast	Yeast
CSB-CF007139RA	Recombinant Rat Dipeptidyl peptidase 4 (Dpp4),Partial	in vitro E.coli expression system
CSB-EP007139RA	Recombinant Rat Dipeptidyl peptidase 4 (Dpp4), partial	E.coli
CSB-BP007139RA CSB-MP007139RA CSB-EP007139RA-B	Recombinant Rat Dipeptidyl peptidase 4 (Dpp4), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF007139RA(F2)	Recombinant Rat Dipeptidyl peptidase 4 (Dpp4), partial	in vitro E.coli expression system

DPP4 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP007139MO	Recombinant Mouse Dipeptidyl peptidase 4 (Dpp4), partial,Yeast	Yeast
CSB-CF007139MO	Recombinant Mouse Dipeptidyl peptidase 4 (Dpp4), partial	in vitro E.coli expression system
CSB-EP007139MO CSB-BP007139MO CSB-MP007139MO CSB-EP007139MO-B	Recombinant Mouse Dipeptidyl peptidase 4 (Dpp4), partial	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Trichophyton equinum (Horse ringworm fungus)

Code	Product Name	Source
CSB-YP007139TPZ CSB-EP007139TPZ CSB-BP007139TPZ CSB-MP007139TPZ CSB-EP007139TPZ-B	Recombinant Trichophyton equinum Dipeptidyl peptidase 4 (DPP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Trichophyton tonsurans (Scalp ringworm fungus)

Code	Product Name	Source
CSB-YP007139TQB CSB-EP007139TQB CSB-BP007139TQB CSB-MP007139TQB CSB-EP007139TQB-B	Recombinant Trichophyton tonsurans Dipeptidyl peptidase 4 (DPP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)

Code	Product Name	Source
CSB-YP007139DOP CSB-EP007139DOP CSB-BP007139DOP CSB-MP007139DOP CSB-EP007139DOP-B	Recombinant Arthroderma otae Dipeptidyl peptidase 4 (DPP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)

Code	Product Name	Source
CSB-YP373018AVC CSB-EP373018AVC CSB-BP373018AVC CSB-MP373018AVC CSB-EP373018AVC-B	Recombinant Aspergillus clavatus Probable dipeptidyl peptidase 4 (dpp4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)

Code	Product Name	Source
CSB-YP373094NEZ CSB-EP373094NEZ CSB-BP373094NEZ CSB-MP373094NEZ CSB-EP373094NEZ-B	Recombinant Neosartorya fischeri Probable dipeptidyl peptidase 4 (dpp4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)

Code	Product Name	Source
CSB-YP493963DOX CSB-EP493963DOX CSB-BP493963DOX CSB-MP493963DOX CSB-EP493963DOX-B	Recombinant Aspergillus flavus Probable dipeptidyl peptidase 4 (dpp4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)

Code	Product Name	Source
CSB-YP514306DOM CSB-EP514306DOM CSB-BP514306DOM CSB-MP514306DOM CSB-EP514306DOM-B	Recombinant Arthroderma benhamiae Probable dipeptidyl peptidase 4 (DPP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Trichophyton verrucosum (strain HKI 0517)

Code	Product Name	Source
CSB-YP520382TQC CSB-EP520382TQC CSB-BP520382TQC CSB-MP520382TQC CSB-EP520382TQC-B	Recombinant Trichophyton verrucosum Probable dipeptidyl peptidase 4 (DPP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)

Code	Product Name	Source
CSB-YP534014NGT CSB-EP534014NGT CSB-BP534014NGT CSB-MP534014NGT CSB-EP534014NGT-B	Recombinant Neosartorya fumigata Probable dipeptidyl peptidase 4 (dpp4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)

Code	Product Name	Source
CSB-YP647242DPA CSB-EP647242DPA CSB-BP647242DPA CSB-MP647242DPA CSB-EP647242DPA-B	Recombinant Aspergillus oryzae Dipeptidyl peptidase 4 (dpp4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)

Code	Product Name	Source
CSB-YP688495EKF CSB-EP688495EKF CSB-BP688495EKF CSB-MP688495EKF CSB-EP688495EKF-B	Recombinant Emericella nidulans Probable dipeptidyl peptidase 4 (dpp4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Trichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum)

Code	Product Name	Source
CSB-YP689284TQA CSB-EP689284TQA CSB-BP689284TQA CSB-MP689284TQA CSB-EP689284TQA-B	Recombinant Trichophyton rubrum Dipeptidyl peptidase 4 (DPP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)

Code	Product Name	Source
CSB-YP700398NGS CSB-EP700398NGS CSB-BP700398NGS CSB-MP700398NGS CSB-EP700398NGS-B	Recombinant Neosartorya fumigata Probable dipeptidyl peptidase 4 (dpp4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Source
CSB-YP882019CA CSB-EP882019CA CSB-BP882019CA CSB-MP882019CA CSB-EP882019CA-B	Recombinant Cat Dipeptidyl peptidase 4 (DPP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-CF007139BO	Recombinant Bovine Dipeptidyl peptidase 4 (DPP4)	in vitro E.coli expression system
CSB-YP007139BO1 CSB-EP007139BO1 CSB-BP007139BO1 CSB-MP007139BO1 CSB-EP007139BO1-B	Recombinant Bovine Dipeptidyl peptidase 4 (DPP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-CF007139PI	Recombinant Pig Dipeptidyl peptidase 4 (DPP4)	in vitro E.coli expression system
CSB-YP007139PI1 CSB-EP007139PI1 CSB-BP007139PI1 CSB-MP007139PI1 CSB-EP007139PI1-B	Recombinant Pig Dipeptidyl peptidase 4 (DPP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DPP4 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF007139HU	Recombinant Human Dipeptidyl peptidase 4 (DPP4)	in vitro E.coli expression system
CSB-EP007139HU1	Recombinant Human Dipeptidyl peptidase 4 (DPP4), partial,Escherichia Coli	E.coli
CSB-BP007139HU1	Recombinant Human Dipeptidyl peptidase 4 (DPP4), partial,Baculovirus	Baculovirus
CSB-YP007139HU1	Recombinant Human Dipeptidyl peptidase 4 (DPP4), partial	Yeast
CSB-MP007139HU1	Recombinant Human Dipeptidyl peptidase 4 (DPP4), partial	Mammalian cell