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Insulin-like growth factor 1 receptor is a protein in humans that is encoded by IGF1R gene. Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell.
The following IGF1R reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IGF1R Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA011087GA01HU | IGF1R Antibody |
Human,Mouse,Rat | ELISA,WB,IP |
| CSB-PA597654 | Phospho-IGF1R (Tyr1165/Tyr1166) Antibody |
Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA067618 | IGF1R (Ab-1161) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA142373 | IGF1R (Ab-1165/1166) Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA443662 | IGF1R (Ab-1280) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA449888 | Phospho-IGF1R (Tyr1280) Antibody |
Human | ELISA,WB |
| CSB-PA277594 | IGF1R (Ab-1346) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA120059 | Phospho-IGF1R (Tyr1161) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA945418 | Phospho-IGF1R (Tyr1346) Antibody |
Human,Mouse,Rat | ELISA,IHC |
| CSB-PA942675 | IGF1R (Ab-1346) Antibody |
Human,Mouse | ELISA,WB,IHC |
| CSB-PA000549 | Phospho-IGF1R (Y1165/Y1166) Antibody |
Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA009487 | Phospho-IGF1R (Y1346) Antibody |
Human,Mouse,Rat | IHC, ELISA |
| CSB-PA009488 | IGF1R Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA009489 | IGF1R Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA009490 | IGF1R Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA08395A0Rb | IGF1R Antibody |
Human | ELISA, IF |
| CSB-PA08395B0Rb | IGF1R Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA08395D0Rb | IGF1R Antibody, Biotin conjugated |
Human | ELISA |
IGF1R Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-BP011087HU |
Recombinant Human Insulin-like growth factor 1 receptor (IGF1R), partial |
Baculovirus |
| CSB-EP011087HUa0 | Recombinant Human Insulin-like growth factor 1 receptor (IGF1R), partial |
E.coli |
| CSB-MP011087HU | Recombinant Human Insulin-like growth factor 1 receptor (IGF1R), partial |
Mammalian cell |
| CSB-YP011087HU | Recombinant Human Insulin-like growth factor 1 receptor (IGF1R), partial |
Yeast |
| CSB-EP011087HU | Recombinant Human Insulin-like growth factor 1 receptor (IGF1R), partial |
E.coli |
IGF1R Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP011087MO CSB-EP011087MO CSB-BP011087MO CSB-MP011087MO CSB-EP011087MO-B |
Recombinant Mouse Insulin-like growth factor 1 receptor (Igf1r), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1R Proteins for Sus scrofa (Pig)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP011087PI CSB-EP011087PI CSB-BP011087PI CSB-MP011087PI CSB-EP011087PI-B |
Recombinant Pig Insulin-like growth factor 1 receptor (IGF1R), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1R Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF011087XBE | Recombinant Xenopus laevis Insulin-like growth factor 1 receptor (igf1r) |
in vitro E.coli expression system |
| CSB-YP011087XBE1 CSB-EP011087XBE1 CSB-BP011087XBE1 CSB-MP011087XBE1 CSB-EP011087XBE1-B |
Recombinant Xenopus laevis Insulin-like growth factor 1 receptor (igf1r), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1R Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF011087RA | Recombinant Rat Insulin-like growth factor 1 receptor (Igf1r) |
in vitro E.coli expression system |
| CSB-EP011087RA1 | Recombinant Rat Insulin-like growth factor 1 receptor (Igf1r), partial,Escherichia Coli |
E.coli |
| CSB-BP011087RA1 | Recombinant Rat Insulin-like growth factor 1 receptor (Igf1r), partial,Baculovirus |
Baculovirus |
| CSB-MP011087RA1 | Recombinant Rat Insulin-like growth factor 1 receptor (Igf1r), partial,Mammalian cell |
Mammalian cell |
| CSB-YP011087RA1 | Recombinant Rat Insulin-like growth factor 1 receptor (Igf1r), partial,Yeast |
Yeast |
IGF1R ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E13766h | Human insulin-like growth factors 1 receptor,IGF-1R ELISA Kit |
serum, plasma, tissue homogenates | 0.078 ng/mL |
IGF1R ELISA Kit for Rattus norvegicus (Rat)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E13873r | Rat Insulin-like Growth Factors 1 Receptor,IGF-1R ELISA Kit |
serum, plasma, tissue homogenates | 0.8 pg/mL |
The insulin-like growth factor 1 receptor is a protein in humans that is encoded by the IGF1R gene. The IGF1R protein is a receptor tyrosine kinase that mediates the actions of insulin-like growth factor 1 (IGF1). It binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of the malignant cell. IGF-1 plays an important role in the growth and continues to have anabolic effects in adults – meaning that it can induce hypertrophy of and other target tissues. Mice lacking the IGF-1 receptor died late in development, and exhibited a dramatic reduction in body mass, testifying to the strong growth-promoting effect of this receptor.
