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Phosphatidylinositol 3-kinase regulatory subunit beta is a protein in humans that is encoded by PIK3R2 gene. Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
The following PIK3R2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PIK3R2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA003770 | PIK3R2 Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA030059 | Phospho-PIK3R2 (Y464) Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA030060 | PIK3R2 Antibody |
Human,Mouse,Rat | IHC, ELISA |
| CSB-PA080215 | PIK3R2 Antibody |
Human | WB, IHC |
| CSB-PA797994 | PIK3R2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA190895 | PIK3R2 Antibody |
Human,Mouse,Rat | IHC,ELISA |
| CSB-PA018005LA01HU | PIK3R2 Antibody |
Human | ELISA, WB, IHC |
| CSB-PA018005LB01HU | PIK3R2 Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA018005LC01HU | PIK3R2 Antibody, FITC conjugated |
Human | |
| CSB-PA018005LD01HU | PIK3R2 Antibody, Biotin conjugated |
Human | ELISA |
PIK3R2 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP018005BO CSB-EP018005BO CSB-BP018005BO CSB-MP018005BO CSB-EP018005BO-B |
Recombinant Bovine Phosphatidylinositol 3-kinase regulatory subunit beta (PIK3R2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3R2 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP018005MO CSB-EP018005MO CSB-BP018005MO CSB-MP018005MO CSB-EP018005MO-B |
Recombinant Mouse Phosphatidylinositol 3-kinase regulatory subunit beta (Pik3r2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3R2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP018005HU CSB-EP018005HU CSB-BP018005HU CSB-MP018005HU CSB-EP018005HU-B |
Recombinant Human Phosphatidylinositol 3-kinase regulatory subunit beta (PIK3R2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3R2 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP730925RA CSB-EP730925RA CSB-BP730925RA CSB-MP730925RA CSB-EP730925RA-B |
Recombinant Rat Phosphatidylinositol 3-kinase regulatory subunit beta (Pik3r2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Phosphatidylinositol 3-kinase regulatory subunit beta is a protein in humans that is encoded by PIK3R2 gene. It is a regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
