Your Good Partner in Biology Research
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Your Good Partner in Biology Research
| Code | CSB-PA018005LA01HU |
| See More Details |  |
| Size |
US$299Purchase it in Cusabio online store (Shop online in the US. Customers outside the US, please order from local distributors.) |
| Uniprot No. | O00459 |
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| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
| Immunogen | Recombinant Human Phosphatidylinositol 3-kinase regulatory subunit beta protein (75-125AA) |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200 |
| Relevance | Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (PubMed:23604317). Promotes nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity). |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method | >95%, Protein G purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta), PIK3R2 |
| Immunogen Species | Human |
| Research Area | Signal Transduction |
| Target Names | PIK3R2 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
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PIK3R2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA018005LB01HU | PIK3R2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA003770 | PIK3R2 Antibody | Human,Mouse,Rat | WB,ELISA |
| CSB-PA030059 | Phospho-PIK3R2 (Y464) Antibody | Human,Mouse,Rat | WB,ELISA |
| CSB-PA030060 | PIK3R2 Antibody | Human,Mouse,Rat | IHC,ELISA |
| CSB-PA080215 | PIK3R2 Antibody | Human | WB,IHC |
| CSB-PA797994 | PIK3R2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA018005LD01HU | PIK3R2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA018005LC01HU | PIK3R2 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA190895 | PIK3R2 Antibody | Human,Mouse,Rat | IHC,ELISA |
PIK3R2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP018005HU CSB-EP018005HU CSB-BP018005HU CSB-MP018005HU |
Recombinant Human Phosphatidylinositol 3-kinase regulatory subunit beta(PIK3R2) | Yeast E.coli Baculovirus Mammalian cell |
PIK3R2 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL018005HU | Human Phosphatidylinositol 3-kinase regulatory subunit beta(PIK3R2) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 5.86 pg/mL |
2-hydroxyisobutyryl-HIST1H3A (K18) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H4A (K5) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
