Recombinant Rhesus Macaque Interleukin-13 protein(IL13) (Active)

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Code CSB-AP003181MOW
Product Type Interleukin
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Uniprot No. Q864V6
Lead Time 5-10 business days
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Storage Buffer 0.2 μm filtered PBS, pH 7.4, 3% trehalose ,lyophilized
Alias IL-13
Species Macaca mulatta (Rhesus macaque)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 5 ng/ml, corresponding to a specific activity of >2.0x105 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence SPSPVPRSTA LKELIEELVN ITQNQKAPLC NGSMVWSINL TAGVYCAALE SLINVSGCSA IEKTQRMLNG FCPHKVSAGQ FSSLRVRDTK IEVAQFVKDL LVHLKKLFRE GRFN
Research Area Immunology
Source E.coli
Gene Names IL13
Expression Region 19-132aa
Tag Info Tag-Free
Mol. Weight 12.6 kDa
Protein Description Full Length of Mature Protein
PubMed ID 1724381
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Function Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages.
Subcellular Location Secreted
Protein Families IL-4/IL-13 family
Database Links

KEGG: mcc:574325

UniGene: Mmu.3675

Pathway Jak-STAT signaling pathway
Fc epsilon RI signaling pathway
IL-17 signaling pathway
Th1 and Th2 cell differentiation

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