CD247 Research Reagents

T-cell surface glycoprotein CD3 zeta chain is a protein in humans that is encoded by CD247 gene. Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways.

The following CD247 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CD247 Antibodies

CD247 Antibodies for Homo sapiens (Human)

CD247 Proteins

CD247 Proteins for Oryctolagus cuniculus (Rabbit)

CD247 Proteins for Sus scrofa (Pig)

CD247 Proteins for Homo sapiens (Human)

CD247 Proteins for Ovis aries (Sheep)


CD247 ELISA Kit for Homo sapiens (Human)

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