CD247

T-cell surface glycoprotein CD3 zeta chain is a protein in humans that is encoded by CD247 gene. Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways.

CD247 Antibodies

CD247 Antibodies for Homo sapiens (Human)

CD247 Proteins

CD247 Proteins for Oryctolagus cuniculus (Rabbit)

CD247 Proteins for Sus scrofa (Pig)

CD247 Proteins for Homo sapiens (Human)

CD247 Proteins for Ovis aries (Sheep)

CD247 ELISA Kit

CD247 ELISA Kit for Homo sapiens (Human)

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

© 2007-2020 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1