CHI3L1

CHI3L1, also known as chitinase-3-like protein 1, is commonly referred to as YKL-40. This protein is involved in a variety of biological processes. It exerts its effects by binding to specific receptors, thereby activating multiple signaling pathways, such as the PI3K/Akt and MAPK pathways.
Elevated levels of CHI3L1 have been associated with several diseases, including asthma, arthritis, and certain types of cancer. In drug development, there have been efforts to target CHI3L1 to develop novel therapeutics. Some potential inhibitors are under pre - clinical and clinical investigation to explore their effectiveness in treating related diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP005346HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) CHI3L1.

Human Chitinase-3-like Protein 1(YKL-40/CHI3L1)ELISA Kit (CSB-E13608h)

Validated Data

Code: CSB-E13608h

Size: 96T,5×96T,10×96T

Sensitivity: 78.065 pg/mL

Detection Range: 46.875 pg/mL-3000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following CHI3L1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CHI3L1 Antibodies

CHI3L1 Proteins

CHI3L1 ELISA Kits

CHI3L1 Antibodies

CHI3L1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA005346ZA01HU	CHI3L1 Antibody	Homo sapiens	ELISA, WB (ensure identification of antigen)

CHI3L1 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA893408ZA01RA	Chi3l1 Antibody	Rattus norvegicus	ELISA, WB (ensure identification of antigen)

CHI3L1 Proteins

CHI3L1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP005346BO CSB-EP005346BO CSB-BP005346BO CSB-MP005346BO CSB-EP005346BO-B	Recombinant Bovine Chitinase-3-like protein 1 (CHI3L1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHI3L1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP005346HU CSB-BP005346HU CSB-MP005346HU CSB-EP005346HU-B	Recombinant Human Chitinase-3-like protein 1 (CHI3L1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP005346HU	Recombinant Human Chitinase-3-like protein 1 (CHI3L1)	E.coli

CHI3L1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP642759PI CSB-EP642759PI CSB-BP642759PI CSB-MP642759PI CSB-EP642759PI-B	Recombinant Pig Chitinase-3-like protein 1 (CHI3L1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHI3L1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP720246MO CSB-EP720246MO CSB-BP720246MO CSB-MP720246MO CSB-EP720246MO-B	Recombinant Mouse Chitinase-3-like protein 1 (Chi3l1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHI3L1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP732741PYX CSB-EP732741PYX CSB-BP732741PYX CSB-MP732741PYX CSB-EP732741PYX-B	Recombinant Pongo abelii Chitinase-3-like protein 1 (CHI3L1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHI3L1 Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP744230SH CSB-EP744230SH CSB-BP744230SH CSB-MP744230SH CSB-EP744230SH-B	Recombinant Sheep Chitinase-3-like protein 1 (CHI3L1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHI3L1 Proteins for Bubalus bubalis (Domestic water buffalo)

Code	Product Name	Source
CSB-YP767178BWX CSB-EP767178BWX CSB-BP767178BWX CSB-MP767178BWX CSB-EP767178BWX-B	Recombinant Bubalus bubalis Chitinase-3-like protein 1 (CHI3L1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHI3L1 Proteins for Capra hircus (Goat)

Code	Product Name	Source
CSB-YP844620GO CSB-EP844620GO CSB-BP844620GO CSB-MP844620GO CSB-EP844620GO-B	Recombinant Goat Chitinase-3-like protein 1 (CHI3L1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHI3L1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP893408RA CSB-BP893408RA CSB-MP893408RA CSB-EP893408RA-B	Recombinant Rat Chitinase-3-like protein 1 (Chi3l1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP893408RAb1	Recombinant Rat Chitinase-3-like protein 1 (Chi3l1)	E.coli
CSB-EP893408RA	Recombinant Rat Chitinase-3-like protein 1 (Chi3l1)	E.coli