CXCL10, also recognized under aliases such as IP-10 and crg-2, is a cytokine of the CXC chemokine family, typically produced by various cells in response to interferon-gamma (IFN-γ). Its primary function is to trigger chemotaxis by engaging with the CXCR3 receptor, thereby directing the migration of immune cells like monocytes, natural killer cells, and T cells to sites of inflammation or infection. CXCL10 plays a role in immune response regulation, enhancement of cell adhesion, anti-tumor activity, and inhibition of bone marrow colony formation and angiogenesis. It features in the pathology of conditions such as malignant tumors and viral hepatitis, with its expression levels being indicative of disease severity and prognosis.
Recombinant Human C-X-C motif chemokine 10 protein (CXCL10) (Active) (CSB-AP000721HU)
Validated Data
CXCL10 Recombinant Monoclonal Antibody (CSB-RA903061A0HU)
Validated Data
IHC image of CSB-RA903061A0HU diluted at 1:100 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
The following CXCL10 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CXCL10 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA06107C0Rb | CXCL10 Antibody, FITC conjugated | Human | |
CSB-PA06107A0Rb | CXCL10 Antibody | Human | ELISA |
CSB-PA06107B0Rb | CXCL10 Antibody, HRP conjugated | Human | ELISA |
CSB-PA761371 | CXCL10 Antibody | Human | IHC, ELISA |
CSB-RA903061A0HU | CXCL10 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
CXCL10 Antibodies for Macaca mulatta (Rhesus macaque)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA822646LA01MOW | CXCL10 Antibody | Macaca mulatta | ELISA |
CXCL10 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA006240ZA01MO | Cxcl10 Antibody | Mus musculus | ELISA, WB (ensure identification of antigen) |
CXCL10 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP006240MO CSB-BP006240MO CSB-MP006240MO CSB-EP006240MO-B |
Recombinant Mouse C-X-C motif chemokine 10 (Cxcl10) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP001141MO | Recombinant Mouse C-X-C motif chemokine 10 protein (Cxcl10) | E.Coli |
CSB-EP006240MO | Recombinant Mouse C-X-C motif chemokine 10 (Cxcl10) | E.coli |
CXCL10 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP006240RA CSB-EP006240RA CSB-BP006240RA CSB-MP006240RA CSB-EP006240RA-B |
Recombinant Rat C-X-C motif chemokine 10 (Cxcl10) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP001451RA | Recombinant Rat C-X-C motif chemokine 10 protein (Cxcl10) (Active) | E.coli |
CXCL10 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP006240HU | Recombinant Human C-X-C motif chemokine 10 (CXCL10) | Yeast |
CSB-AP000721HU | Recombinant Human C-X-C motif chemokine 10 protein (CXCL10) (Active) | E.coli |
CSB-MP006240HU | Recombinant Human C-X-C motif chemokine 10 (CXCL10) | Mammalian cell |
CSB-BP006240HU CSB-EP006240HU-B |
Recombinant Human C-X-C motif chemokine 10 (CXCL10) | Baculovirus In Vivo Biotinylation in E.coli |
CSB-RP061074h | Recombinant Human C-X-C motif chemokine 10 protein (CXCL10) | E.coli |
CSB-EP006240HUc7 | Recombinant Human C-X-C motif chemokine 10 (CXCL10) | E.coli |
CSB-AP003501HU | Recombinant Human C-X-C motif chemokine 10 (CXCL10) (Active) | E.coli |
CSB-EP006240HU | Recombinant Human C-X-C motif chemokine 10 protein (CXCL10) | E.coli |
CXCL10 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP644427BO CSB-EP644427BO CSB-BP644427BO CSB-MP644427BO CSB-EP644427BO-B |
Recombinant Bovine C-X-C motif chemokine 10 (CXCL10) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL10 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-YP689357DO CSB-EP689357DO CSB-BP689357DO CSB-MP689357DO CSB-EP689357DO-B |
Recombinant Dog C-X-C motif chemokine 10 (CXCL10) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL10 Proteins for Macaca nemestrina (Pig-tailed macaque)
Code | Product Name | Source |
---|---|---|
CSB-YP803036MOX CSB-EP803036MOX CSB-BP803036MOX CSB-MP803036MOX CSB-EP803036MOX-B |
Recombinant Macaca nemestrina C-X-C motif chemokine 10 (CXCL10) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL10 Proteins for Macaca mulatta (Rhesus macaque)
Code | Product Name | Source |
---|---|---|
CSB-YP822646MOW CSB-BP822646MOW CSB-MP822646MOW CSB-EP822646MOW-B |
Recombinant Macaca mulatta C-X-C motif chemokine 10 (CXCL10) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP822646MOW | Recombinant Macaca mulatta C-X-C motif chemokine 10 (CXCL10) | E.coli |
CSB-AP001031MOW | Recombinant Macaca mulatta C-X-C motif chemokine 10 protein (CXCL10) | E.Coli |
CXCL10 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08181h | Human interferon-inducible protein 10,IP-10 ELISA Kit | serum, plasma, tissue homogenates | 7.8 pg/mL |
CSB-E08181h-IS | Human interferon-inducible protein 10,IP-10 ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
CXCL10 ELISA Kit for Monkey
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL006240RH | Monkey C-X-C motif chemokine 10(CXCL10) ELISA kit | serum, plasma, tissue homogenates | 15.6 pg/mL |
CXCL10 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08183m | Mouse interferon-inducible protein 10,IP-10 ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/ml |
CXCL10 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08182r | Rat interferon-inducible protein 10,IP-10 ELISA Kit | serum, plasma, tissue homogenates | 195 pg/mL |