E2F1 Research Reagents

Transcription factor E2F1 is a protein in humans that is encoded by E2F1 gene. Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters

The following E2F1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

E2F1 Antibodies

E2F1 Antibodies for Homo sapiens (Human)

E2F1 Antibodies for Drosophila melanogaster (Fruit fly)

E2F1 Proteins

E2F1 Proteins for Rattus norvegicus (Rat)

E2F1 Proteins for Drosophila melanogaster (Fruit fly)

E2F1 Proteins for Mus musculus (Mouse)

E2F1 Proteins for Gallus gallus (Chicken)

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