TNFSF11, a member of the tumor necrosis factor superfamily 11, is a crucial cytokine for bone metabolism, immune system function, and tumor biology. Produced by T cells, it activates the NF-κB signaling pathway by binding to its receptor RANK, promoting osteoclast differentiation and activity, and affecting bone resorption. Abnormal TNFSF11 expression is related to osteoporosis, bone metastatic cancer, and may promote tumor cell invasion and metastasis in the tumor microenvironment.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TNFSF11 Antibody (CSB-PA023986LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA023986LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023986LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA023986LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following TNFSF11 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TNFSF11 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA07964A0Rb | Tnfsf11 Antibody | Mouse | ELISA |
CSB-PA07964C0Rb | Tnfsf11 Antibody, FITC conjugated | Mouse | |
CSB-PA07964D0Rb | Tnfsf11 Antibody, Biotin conjugated | Mouse | ELISA |
CSB-PA023986LA01MO | Tnfsf11 Antibody | Mouse | ELISA, IF |
CSB-PA023986LB01MO | Tnfsf11 Antibody, HRP conjugated | Mouse | ELISA |
CSB-PA023986LC01MO | Tnfsf11 Antibody, FITC conjugated | Mouse | |
CSB-PA023986LD01MO | Tnfsf11 Antibody, Biotin conjugated | Mouse | ELISA |
TNFSF11 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA111246 | TNFSF11 Antibody | Human,Mouse | ELISA,WB,IF |
CSB-PA003937 | TNFSF11 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
CSB-PA005647 | TNFSF11 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA023986LA01HU | TNFSF11 Antibody | Human | ELISA, IHC, IF |
CSB-PA023986LB01HU | TNFSF11 Antibody, HRP conjugated | Human | ELISA |
CSB-PA023986LC01HU | TNFSF11 Antibody, FITC conjugated | Human | |
CSB-PA023986LD01HU | TNFSF11 Antibody, Biotin conjugated | Human | ELISA |
TNFSF11 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP023986MO CSB-BP023986MO CSB-MP023986MO CSB-EP023986MO-B |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 11 (Tnfsf11), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP023986MO | Recombinant Mouse Tumor necrosis factor ligand superfamily member 11 (Tnfsf11), partial | E.coli |
CSB-CF023986MO(A4) | Recombinant Mouse Tumor necrosis factor ligand superfamily member 11 (Tnfsf11) | in vitro E.coli expression system |
CSB-AP005021MO | Recombinant Mouse Tumor necrosis factor ligand superfamily member 11 (Tnfsf11), partial (Active) | Mammalian cell |
TNFSF11 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP023986HU1 CSB-EP023986HU1 CSB-BP023986HU1 CSB-MP023986HU1 CSB-EP023986HU1-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 11 (TNFSF11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF023986HU | Recombinant Human Tumor necrosis factor ligand superfamily member 11 (TNFSF11) | in vitro E.coli expression system |
CSB-AP004851HU | Recombinant Human Tumor necrosis factor ligand superfamily member 11 (TNFSF11), partial (Active) | E.coli |
CSB-MP023986HU(F2) | Recombinant Human Tumor necrosis factor ligand superfamily member 11 (TNFSF11), partial | Mammalian cell |
CSB-MP023986HU(F2)b0 | Recombinant Human Tumor necrosis factor ligand superfamily member 11 (TNFSF11), partial | Mammalian cell |
TNFSF11 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP880653RA CSB-EP880653RA CSB-BP880653RA CSB-MP880653RA CSB-EP880653RA-B |
Recombinant Rat Tumor necrosis factor ligand superfamily member 11 (Tnfsf11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TNFSF11 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E05125h | Human soluble receptor activator of nuclear factor-kB ligand,sRANKL ELISA Kit | serum, plasma, cell culture supeernates, tissue homogenates | 1.95 pg/mL |
TNFSF11 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E05127m | Mouse soluble receptor activator of nuclear factor-kB ligand,sRANKL ELISA Kit | serum, plasma, tissue homogenates. | 3.12 pg/ml. |
TNFSF11 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E05126r | Rat soluble receptor activator of nuclear factor-kB ligand,sRANKL ELISA Kit | serum, plasma, cell culture supernates | 15.6 pg/mL |