Your Good Partner in Biology Research
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Your Good Partner in Biology Research
| Code | CSB-PA08249A0Rb |
| See More Details |  |
| Size |
US$299Purchase it in Cusabio online store (only available for customers from the US) |
| Uniprot No. | P16612 |
| Image |
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| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
| Immunogen | Recombinant Rat Vascular endothelial growth factor A protein (27-232AA) |
| Raised in | Rabbit |
| Species Reactivity | Rat |
| Tested Applications | ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200 |
| Relevance | Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method | >95%, Protein G purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Vascular endothelial growth factor A (VEGF-A) (Vascular permeability factor) (VPF), Vegfa, Vegf |
| Immunogen Species | Rat |
| Research Area | Cardiovascular |
| Target Names | Vegfa |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
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| Function | Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). |
| Subcellular Location | Secreted |
| Protein Families | PDGF/VEGF growth factor family |
| Tissue Specificity | Expressed in the pituitary, in brain, in particularly in supraoptic and paraventricular nuclei and the choroid plexus. Also found abundantly in the corpus luteum of the ovary and in kidney glomeruli. Expressed in the ductal epithelial cells of post-pubert |
| Database Links |
KEGG: rno:83785 STRING: 10116.ENSRNOP00000026637 UniGene: Rn.1923 |
| Pathway |
HIF-1 signaling pathway
MAPK signaling pathway PI3K-Akt signaling pathway VEGF signaling pathway Focal adhesion Ras signaling pathway AGE-RAGE signaling pathway in diabetic complications Rap1 signaling pathway |
Vegfa Antibodies for Rattus norvegicus (Rat)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA08249B0Rb | Vegfa Antibody, HRP conjugated | Rat | ELISA |
| CSB-PA08249D0Rb | Vegfa Antibody, Biotin conjugated | Rat | ELISA |
| CSB-PA08249C0Rb | Vegfa Antibody, FITC conjugated | Rat | ELISA |
Vegfa Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP025833RA CSB-BP025833RA CSB-MP025833RA |
Recombinant Rat Vascular endothelial growth factor A(Vegfa) | Yeast Baculovirus Mammalian cell |
| CSB-EP025833RA | Recombinant Rat Vascular endothelial growth factor A(Vegfa) | E.coli |
Vegfa ELISA Kit for Rattus norvegicus (Rat)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E04757r | Rat Vascular Endothelial cell Growth Factor,VEGF ELISA Kit | serum, plasma, tissue homogenates | 0.97 pg/mL |
2-hydroxyisobutyryl-HIST1H3A (K18) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
