Code | CSB-RA578819A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IF | 1:20-1:200 |
PIK3CA is a critical component of the PI3K pathway that is involved in carcinogenesis and metastasis. It regulates tumor growth and progression through the PI3K pathway. Somatic mutations in PIK3CA can generally be found in several types of cancer, including brain, breast, liver, and colon carcinomas. Overexpression of PIK3CA facilitates epithelial‐to‐mesenchymal transition (EMT) and enriches the cancer stem cell (CSC) population. PIK3CA gene alteration and PIK3CA upregulation are frequently been detected in bladder cancer and promote the proliferation, invasion, and metastasis of bladder cancer cells.
The main steps in the production of this PIK3CA recombinant antibody include immunization; harvest of positive spleen cells; obtaining the antibody sequence by screening and sequencing; expression of the target antibody in mammalian cells; purification. The PIK3CA antibody was produced recombinantly and has many advantages: high reproducibility, specificity and scalability. And has been validated in ELISA, WB, IF.There are currently no reviews for this product.