PIK3CA

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform is a protein in humans that is encoded by PIK3CA gene. Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinases ligands such as EGF, insulin, IGF1, VEGFA and PDGF. Involved in signaling via insulin-receptor substrate (IRS) proteins.

PIK3CA Antibodies

PIK3CA Antibodies for Homo sapiens (Human)

PIK3CA Antibodies for Human

PIK3CA Proteins

PIK3CA Proteins for Bos taurus (Bovine)

PIK3CA Proteins for Homo sapiens (Human)

PIK3CA Proteins for Mus musculus (Mouse)

PIK3CA ELISA Kit

PIK3CA ELISA Kit for Mus musculus (Mouse)

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