Code | CSB-RA898030A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:5000 |
RHOA, a member of the RHO GTPase enzyme family, is a crucial intracellular modulator of dynamics and other functions, including adhesion, proliferation, survival, and gene expression. It takes part in the entire process of cancer progression and plays an important role in tumor cell proliferation, survival and progression, regulating the formation of epithelial polarity, junction assembly, and disruption of epithelial cells. The activation of the RHOA-ROCK signaling pathway is important for both amoeboid and mesenchymal migration. Lamellipodia and uropods are absent in RHOA-depleted cells, which instead feature narrow protrusions projecting from a rounded cell body.
The main steps in the production of this RHOA recombinant antibody include immunization; harvest of positive spleen cells; obtaining the antibody sequence by screening and sequencing; expression of the target antibody in mammalian cells; purification. The RHOA antibody was produced recombinantly and has many advantages: high reproducibility, specificity and scalability. And has been validated in ELISA, WB.There are currently no reviews for this product.