Code | CSB-RA024077MA1HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:1000-1:5000 |
IF | 1:20-1:200 |
FC | 1:20-1:200 |
The process for creating the TP53 recombinant monoclonal antibody begins by obtaining the TP53 antibody genes, which are then introduced into suitable host cells. These cells serve as the foundation for synthesizing TP53 antibodies using a cell-based expression and translation system. This method offers multiple advantages, notably enhancing the purity and stability of the resultant TP53 recombinant monoclonal antibodies, as well as elevating their affinity and specificity. Post-synthesis, the TP53 recombinant monoclonal antibody goes through a purification stage involving affinity chromatography. Subsequently, it undergoes comprehensive testing, including ELISA, WB, IF, and FC assays. This antibody exclusively targets the human TP53 protein.
TP53 is a critical protein involved in maintaining genomic integrity and preventing the formation of cancer. Its functions include cell cycle regulation, DNA repair, apoptosis induction, and various other roles in response to cellular stress. Mutations in the TP53 gene are commonly associated with a higher risk of cancer development due to the loss of its tumor suppressor functions.
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