AP-2 complex subunit mu is a protein in humans that is encoded by AP2M1 gene. Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation.

AP2M1 Antibodies

AP2M1 Antibodies for Homo sapiens (Human)

AP2M1 Proteins

AP2M1 Proteins for Mus musculus (Mouse)

AP2M1 Proteins for Rattus norvegicus (Rat)

AP2M1 Proteins for Bos taurus (Bovine)

AP2M1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

AP2M1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

AP2M1 Proteins for Gallus gallus (Chicken)

AP2M1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

AP2M1 Proteins for Xenopus laevis (African clawed frog)

AP2M1 Proteins for Homo sapiens (Human)


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