Voltage-dependent T-type calcium channel subunit alpha-1I is a protein in humans that is encoded by CACNA1I gene. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle.
The following CACNA1I reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CACNA1I Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
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CSB-PA413190 | CACNA1I Antibody |
Human,Mouse,Rat | IHC,ELISA |
CACNA1I Proteins for Homo sapiens (Human)
Code | Product Name | Source |
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CSB-YP885788HU CSB-EP885788HU CSB-BP885788HU CSB-MP885788HU CSB-EP885788HU-B |
Recombinant Human Voltage-dependent T-type calcium channel subunit alpha-1I (CACNA1I), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |