CERT1, also known as ceramide transfer protein 1, is a protein involved in sphingolipid metabolism. It functions by transferring ceramide from the endoplasmic reticulum to the Golgi apparatus, a crucial step in sphingolipid synthesis. CERT1 mutations can lead to intellectual disability and neurodevelopmental disorders. The protein operates within the sphingolipid signaling pathway, influencing cellular processes such as differentiation, growth, and apoptosis. Current research focuses on developing inhibitors to modulate CERT1 activity, potentially treating related diseases and metabolic disorders.
COL4A3BP Antibody (CSB-PA896912LA01HU)
Validated Data
Western Blot
Positive WB detected in: Mouse kidney tissue, Mouse stomach tissue, Mouse thymus tissue
All lanes: COL4A3BP antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 71, 69, 84 kDa
Observed band size: 71 kDa
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA896912LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA896912LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following CERT1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CERT1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA005744GA01HU | COL4A3BP Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA785654 | COL4A3BP Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA223164 | COL4A3BP Antibody | Human,Mouse | ELISA,IHC |
CSB-PA896912LA01HU | COL4A3BP Antibody | Human, Mouse | ELISA, WB, IHC, IF |
CERT1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP896912HU CSB-EP896912HU CSB-BP896912HU CSB-MP896912HU CSB-EP896912HU-B |
Recombinant Human Collagen type IV alpha-3-binding protein (COL4A3BP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |