CXCR3, or C-X-C motif chemokine receptor 3, is a G protein-coupled receptor predominantly found on activated T lymphocytes, natural killer cells, and dendritic cells. It initiates intracellular signal transduction upon binding to CXC family chemokine ligands like CXCL9, CXCL10, and CXCL11, leading to the directed migration and localization of immune cells to inflammation or infection sites. CXCR3 is crucial for immune response regulation, promotion of cell-mediated immunity, and involvement in chronic inflammation and autoimmune disease development. Furthermore, CXCR3's interaction with its ligands contributes to tumor immune surveillance and immune escape, making it a potential target for immunotherapy and inflammatory disease treatment research.
Recombinant Human C-X-C chemokine receptor type 3 (CXCR3) (CSB-CF006253HUd7)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Validated Data
Western Blot analysis of K562 cells using CXCR-3 Polyclonal Antibody
Western Blot analysis of various cells using CXCR-3 Polyclonal Antibody
The following CXCR3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CXCR3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA001843 | CXCR3 Antibody | Human | WB, ELISA |
CSB-PA005296 | CXCR3 Antibody | Human | WB, ELISA |
CSB-PA989223 | CXCR3 Antibody | Human,Mouse | ELISA,IHC |
CSB-PA212989 | CXCR3 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA580658 | CXCR3 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA168936 | CXCR3 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA006253LA01HU | CXCR3 Antibody | Human | ELISA, WB, IHC, IF |
CSB-PA006253LB01HU | CXCR3 Antibody, HRP conjugated | Human | ELISA |
CSB-PA006253LC01HU | CXCR3 Antibody, FITC conjugated | Human | |
CSB-PA006253LD01HU | CXCR3 Antibody, Biotin conjugated | Human | ELISA |
CXCR3 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA006253ZA01MO | Cxcr3 Antibody | Mus musculus | ELISA, WB (ensure identification of antigen) |
CXCR3 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-CF686404DO | Recombinant Dog C-X-C chemokine receptor type 3 (CXCR3) | in vitro E.coli expression system |
CSB-YP686404DO1 CSB-EP686404DO1 CSB-BP686404DO1 CSB-MP686404DO1 CSB-EP686404DO1-B |
Recombinant Dog C-X-C chemokine receptor type 3 (CXCR3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCR3 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-CF683649BO | Recombinant Bovine C-X-C chemokine receptor type 3 (CXCR3) | in vitro E.coli expression system |
CSB-YP683649BO1 CSB-EP683649BO1 CSB-BP683649BO1 CSB-MP683649BO1 CSB-EP683649BO1-B |
Recombinant Bovine C-X-C chemokine receptor type 3 (CXCR3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCR3 Proteins for Capra hircus (Goat)
Code | Product Name | Source |
---|---|---|
CSB-CF774733GO | Recombinant Goat C-X-C chemokine receptor type 3 (CXCR3) | in vitro E.coli expression system |
CSB-YP774733GO1 CSB-EP774733GO1 CSB-BP774733GO1 CSB-MP774733GO1 CSB-EP774733GO1-B |
Recombinant Goat C-X-C chemokine receptor type 3 (CXCR3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCR3 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF884915RA | Recombinant Rat C-X-C chemokine receptor type 3 (Cxcr3) | in vitro E.coli expression system |
CSB-YP884915RA1 CSB-EP884915RA1 CSB-BP884915RA1 CSB-MP884915RA1 CSB-EP884915RA1-B |
Recombinant Rat C-X-C chemokine receptor type 3 (Cxcr3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCR3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF006253MO | Recombinant Mouse C-X-C chemokine receptor type 3 (Cxcr3) | in vitro E.coli expression system |
CSB-YP006253MO1 CSB-BP006253MO1 CSB-MP006253MO1 CSB-EP006253MO1-B |
Recombinant Mouse C-X-C chemokine receptor type 3 (Cxcr3), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCR3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF006253HU | Recombinant Human C-X-C chemokine receptor type 3 (CXCR3) | in vitro E.coli expression system |
CSB-CF006253HUb0 | Recombinant Human C-X-C chemokine receptor type 3 (CXCR3) | in vitro E.coli expression system |
CSB-EP006253HU1 | Recombinant Human C-X-C chemokine receptor type 3 (CXCR3), partial | E.coli |
CSB-MP006253HU | Recombinant Human C-X-C chemokine receptor type 3 (CXCR3)-VLPs | Mammalian cell |
CSB-CF006253HUd7 | Recombinant Human C-X-C chemokine receptor type 3 (CXCR3) | in vitro E.coli expression system |
CXCR3 Proteins for Mus musculus(Mouse)
Code | Product Name | Source |
---|---|---|
CSB-EP006253MO1 | Recombinant Mouse C-X-C chemokine receptor type 3 (Cxcr3), partial | E.coli |