DNA damage-binding protein 1 is a protein in humans that is encoded by DDB1 gene. Required for DNA repair. Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also appears to function as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

DDB1 Antibodies

DDB1 Antibodies for Homo sapiens (Human)

DDB1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

DDB1 Proteins

DDB1 Proteins for Bos taurus (Bovine)

DDB1 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

DDB1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

DDB1 Proteins for Homo sapiens (Human)

DDB1 Proteins for Mus musculus (Mouse)

DDB1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

DDB1 Proteins for Solanum cheesmaniae (Galapagos Island tomato) (Lycopersicon cheesmaniae)

DDB1 Proteins for Xenopus laevis (African clawed frog)

DDB1 Proteins for Solanum lycopersicum (Tomato) (Lycopersicon esculentum)

DDB1 Proteins for Gallus gallus (Chicken)

DDB1 Proteins for Rattus norvegicus (Rat)


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