GIP, or glucose-dependent insulin-releasing polypeptide, is an incretin hormone secreted by intestinal K cells. It plays a vital role in insulin secretion regulation postprandially. GIP's mechanisms include binding to its receptor and activating signaling pathways that stimulate insulin secretion in a glucose-dependent manner and promote glucagon secretion by islet α cells. GIP contributes to blood glucose regulation and may influence feeding behavior and cognition through the central nervous system, offering cardiovascular protection. However, its insulinotropic effect may be compromised in type 2 diabetes, though glycemic control improvements can restore GIP's regulatory effects.
Recombinant Human Gastric inhibitory polypeptide (GIP) (CSB-EP009434HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA827246(GIP Antibody) at dilution 1/13, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA827246(GIP Antibody) at dilution 1/13, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA827246(GIP Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
Human Glucose dependent insulin releasing polypeptide,GIP ELISA Kit (CSB-E08484h)
Validated Data
Code: CSB-E08484h
Size: 96T,5×96T,10×96T
Sensitivity: 2.5 ng/ml.
Detection Range: 12.5 ng/ml-200 ng/ml.
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following GIP reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GIP Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA095417 | GIP Antibody | Human | ELISA,IHC |
CSB-PA827246 | GIP Antibody | Human | ELISA,WB,IHC |
CSB-PA009434PA01HU | GIP Antibody | Human | ELISA, IHC |
CSB-PA009434PB01HU | GIP Antibody, HRP conjugated | Human | ELISA |
CSB-PA009434PC01HU | GIP Antibody, FITC conjugated | Human | |
CSB-PA009434PD01HU | GIP Antibody, Biotin conjugated | Human | ELISA |
GIP Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP009434HU CSB-BP009434HU CSB-MP009434HU CSB-EP009434HU-B |
Recombinant Human Gastric inhibitory polypeptide (GIP) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP009434HU | Recombinant Human Gastric inhibitory polypeptide (GIP) | E.coli |
GIP ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08484h | Human Glucose dependent insulin releasing polypeptide,GIP ELISA Kit | serum, plasma, tissue homogenates | 2.5 ng/ml. |