GRINA

GRINA encodes the Glutamate Ionotropic Receptor NMDA Type Subunit Associated Protein 1. It has no well - known common aliases. This protein is involved in the NMDA receptor complex, mediating the influx of calcium ions and regulating synaptic plasticity. It participates in the glutamate - mediated signaling pathway, which is crucial for learning and memory.
Mutations in GRINA are associated with neurodevelopmental disorders. In drug development, there is emerging research on targeting this protein to modulate NMDA receptor function, aiming to improve symptoms of related neurological diseases, although no approved drugs directly targeting GRINA are currently on the market.