HAP1

HAP1, short for huntingtin-associated protein 1, is also known as huntingtin-interacting protein 14. This protein is involved in vesicular trafficking and neuronal function. It interacts with huntingtin and may play a role in the pathogenesis of Huntington's disease by modulating the function of huntingtin. The exact mechanism of HAP1 is still under investigation, but it is thought to be related to the regulation of intracellular transport and signaling pathways.
In terms of related diseases, HAP1 has been linked to Huntington's disease and other neurodegenerative disorders. Research on HAP1-targeted drugs is still in the early stages. Scientists are exploring how to regulate HAP1 function to slow down or prevent the progression of related diseases. Future studies are expected to shed more light on its potential as a therapeutic target.

Popular Product:

HAP1 Antibody (CSB-PA010129LA01HU)

Validated Data

Immunofluorescence staining of SH-SY5Y cells with CSB-PA010129LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

The following HAP1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

HAP1 Antibodies

HAP1 Proteins

HAP1 Antibodies

HAP1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA010129LA01HU	HAP1 Antibody	Human	ELISA, IF
CSB-PA010129LB01HU	HAP1 Antibody, HRP conjugated	Human	ELISA
CSB-PA010129LD01HU	HAP1 Antibody, Biotin conjugated	Human	ELISA

HAP1 Proteins

HAP1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP010129HU CSB-EP010129HU CSB-BP010129HU CSB-MP010129HU CSB-EP010129HU-B	Recombinant Human Huntingtin-associated protein 1 (HAP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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