KIF9

KIF9, a member of the kinesin family, hails from human recombinant proteins, specifically a partial sequence recombinant protein tagged with GST. In the biological realm, KIF9 is intimately tied to cilia transport and movement, serving as a key regulatory factor for ciliary function. It plays a role in the regulation of intraciliary material transport, known as IFT, and works in concert with other kinesins like KIF6 to preserve cilia's structural integrity and function. In mammals, the absence of KIF9 can lead to mild hydrocephalus, indicating its role in nervous system development and maintenance, though without significant effects on ciliary beat or lifespan. Research on KIF9 is pivotal for deciphering the molecular mechanisms of ciliary motion, the pathogenesis of related diseases, and for identifying potential therapeutic targets.

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Recombinant Human Kinesin-like protein KIF9 (KIF9)