OVGP1

OVGP1, recognized for its specific expression in the fallopian tubes and alternately known as oviduct specific glycoprotein or oviductin, is a key player in reproduction. OVGP1 protein is active in the secretory cells of the fallopian tubes and is found in the tube's lumen, where it interacts with both sperm and eggs. OVGP1 enhances sperm acquisition, boosts sperm vitality, and increases the chances of sperm-egg binding, which in turn raises fertilization rates and embryo quality. It also helps to prevent polyspermy, contributing to the development of embryos into the blastocyst stage. As a crucial part of the fallopian tube microenvironment, OVGP1 significantly influences early reproductive events and holds promise for advancing assisted reproductive technologies.