P3H1

The protein corresponding to the gene P3H1 is Prolyl 3-hydroxylase 1. It is also commonly known as P3H1. This protein plays a crucial role in collagen synthesis by catalyzing the 3-hydroxylation of specific proline residues. It is involved in the formation and stabilization of the collagen triple helix structure.
P3H1 is associated with the collagen biosynthesis pathway. Mutations in P3H1 have been linked to several connective - tissue disorders, such as recessive osteogenesis imperfecta. In drug development, research is ongoing to target the functions of P3H1 to treat related diseases. However, the progress is still in the pre - clinical and early - stage research phases.