PCGF1 Research Reagents

Polycomb group RING finger protein 1 is a protein in humans that is encoded by PCGF1 gene. Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down-regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility

The following PCGF1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PCGF1 Antibodies

PCGF1 Antibodies for Homo sapiens (Human)

PCGF1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

PCGF1 Proteins

PCGF1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

PCGF1 Proteins for Bos taurus (Bovine)

PCGF1 Proteins for Xenopus laevis (African clawed frog)

PCGF1 Proteins for Rattus norvegicus (Rat)

PCGF1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

PCGF1 Proteins for Mus musculus (Mouse)

PCGF1 Proteins for Homo sapiens (Human)

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