PIEZO2

PIEZO2 encodes the Piezo-type mechanosensitive ion channel component 2 protein. Also known as FAM38B, it is a key mechanosensitive ion channel. It functions by opening in response to mechanical forces, allowing the influx of cations and initiating electrical signals. Piezo2 is involved in the TRPV4 pathway, which plays a crucial role in mechanotransduction.
Abnormalities of PIEZO2 are related to distal arthrogryposis and Gordon syndrome. In terms of drug development, although currently there are no approved drugs specifically targeting Piezo2, research is underway to explore its potential as a therapeutic target for neurological and musculoskeletal diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The following PIEZO2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PIEZO2 Proteins

PIEZO2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP887983HU CSB-BP887983HU CSB-MP887983HU CSB-EP887983HU-B	Recombinant Human Piezo-type mechanosensitive ion channel component 2 (PIEZO2), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP887983HU	Recombinant Human Piezo-type mechanosensitive ion channel component 2 (PIEZO2), partial	E.coli

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PIEZO2

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