PSMA8

PSMA8, prostate-specific membrane antigen 8, alias prostate-specific membrane protein, glutamate carboxypeptidase II, and so on. It is a transmembrane glycoprotein expressed on the membrane of prostate cells and encoded by its own gene in human cells.The mechanism of action of PSMA8 is mainly related to its localization on the cell membrane, which is involved in a variety of biological processes, including cell signaling, cell proliferation and apoptosis, etc. The expression level of PSMA8 is significantly elevated in prostate cancer, and thus it has become an important target for prostate cancer treatment.

PSMA8 has a wide range of biological significance, which is not only involved in the occurrence and development of prostate cancer, but also closely related to tumor invasiveness and metastasis.High expression of PSMA8 correlates with poor prognosis of prostate cancer, making it a potential biomarker for the diagnosis and treatment of prostate cancer. In addition, PSMA8 may be involved in regulating other intracellular signaling pathways, such as the Nrf2 signaling pathway, which affects the cellular antioxidant stress response . Therefore, PSMA8 is an important molecular target in prostate cancer research and treatment.

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Recombinant Human Proteasome subunit alpha type-7-like (PSMA8)