RAPGEF3

Rap guanine nucleotide exchange factor 3 is a protein in humans that is encoded by RAPGEF3 gene. Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.

The following RAPGEF3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

RAPGEF3 Antibodies

RAPGEF3 Proteins

RAPGEF3 Antibodies

RAPGEF3 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA006508	RAPGEF3 Antibody	Human,Mouse,Rat	WB, ELISA

RAPGEF3 Proteins

RAPGEF3 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP019331HU CSB-EP019331HU CSB-BP019331HU CSB-MP019331HU CSB-EP019331HU-B	Recombinant Human Rap guanine nucleotide exchange factor 3 (RAPGEF3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

RAPGEF3 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP844989MO CSB-EP844989MO CSB-BP844989MO CSB-MP844989MO CSB-EP844989MO-B	Recombinant Mouse Rap guanine nucleotide exchange factor 3 (Rapgef3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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