SORCS3

SORCS3 encodes the Sortilin-related VPS10 domain-containing receptor 3 protein. It is also known as Neurotensin receptor 3-like. This protein plays a crucial role in regulating neuronal development and survival. It functions by binding to various ligands and modulating intracellular signaling pathways, such as the MAPK and PI3K pathways.
Alterations in SORCS3 have been associated with several neurological disorders, including Alzheimer's disease and schizophrenia. In drug development, targeting SORCS3 holds potential for treating these diseases. Currently, research is underway to understand its precise role and develop drugs that can modulate its activity to alleviate associated symptoms.