TCF4

TCF4, a nuclear transcription factor from mammalian genomes, binds to DNA using its high mobility group protein domains. It then forms a transcription complex with β-catenin to modulate the Wnt signaling pathway. TCF4 is crucial for cellular activities such as proliferation, differentiation, migration, polarization, and apoptosis, with significant implications in neural development, oncogenesis, and psychiatric disorders. Dysregulation of TCF4 is linked to a range of diseases, including schizophrenia, Pitt Hopkins syndrome, and various cancers, underscoring its role in diverse biological and pathological processes.

Popular Product:

TCF4 Antibody (CSB-PA023302HA01HU)

Validated Data

Western Blot
Positive WB detected in: Mouse liver tissue, Mouse kidney tissue, Mouse brain tissue
All lanes: TCF4 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 72, 55, 49, 66, 65, 58, 68, 64, 70, 69, 63 kDa
Observed band size: 72 kDa

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA023302HA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA023302HA01HU at dilution of 1:100

The following TCF4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TCF4 Antibodies

TCF4 Proteins

TCF4 Antibodies

TCF4 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA090601	TCF4/TCF12 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA023302HA01HU	TCF4 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA023302HB01HU	TCF4 Antibody, HRP conjugated	Human	ELISA
CSB-PA023302HC01HU	TCF4 Antibody, FITC conjugated	Human
CSB-PA023302HD01HU	TCF4 Antibody, Biotin conjugated	Human	ELISA

TCF4 Proteins

TCF4 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP023302HU CSB-EP023302HU CSB-BP023302HU CSB-MP023302HU CSB-EP023302HU-B	Recombinant Human Transcription factor 4 (TCF4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

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