TRABD

TRABD, alias TRABD2B, C6orf170.TRABD is a protein conserved in humans and a variety of other organisms and is located on chromosome 22q13.33. It has been implicated in a variety of intracellular signaling processes, particularly related to inflammatory and immune responses.The mechanism of action of TRABD involves interactions with TRAF2 and NCF family proteins, which play key roles in the regulation of the NF-κB signaling pathway.TRABD, through its interactions with these proteins, may be involved in the modulation of oxidative stress and inflammatory responses in cells, which affect cellular survival and death.

The biological significance of TRABD is mainly reflected in its involvement in regulating cellular responses to external stimuli. It may be involved in cellular immune response and inflammatory processes by affecting the activation of the NF-κB signaling pathway. In addition, TRABD may also be related to cellular redox homeostasis and involved in the regulation of cellular antioxidant responses. Due to its potential role in cell signaling, TRABD may play a role in the development of certain diseases, including autoimmune diseases and certain types of cancer. Thus, the study of TRABD contributes to our understanding of the complexity of cell signaling and may provide new targets for the treatment of related diseases.

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Recombinant Bovine TraB domain-containing protein (TRABD)