ZCCHC12

ZCCHC12, a protein with a zinc finger CCHC domain, is found in the nucleus and plays a role in RNA metabolism, including transcriptional processes and RNA breakdown. ZCCHC12 exerts its effects through interactions with SMAD1, thereby amplifying bone morphogenetic protein (BMP) signaling, which influences cellular proliferation and the apoptotic pathway. Dysregulation of ZCCHC12 expression is linked to the genesis and progression of a spectrum of tumors, with a particular emphasis on thyroid cancer. Overexpression of this protein is known to stimulate cancer cell proliferation and impede apoptosis. Furthermore, ZCCHC12 is recognized as a promising candidate for diagnostic biomarkers and therapeutic targets in the medical field, aiding in the detection and management of cancer and other diseases.

Popular Product:

Recombinant Human Zinc finger CCHC domain-containing protein 12 (ZCCHC12)