Zfp503

Zfp50 is a transcription factor predominantly expressed in the nervous system. Within the nucleus, it modulates gene expression by binding to DNA and influences the transition from the G1 to G0 phase, which is critical for neural precursor cell differentiation and proliferation. Zfp503 is particularly influential in striatal development, where it promotes D1 type medium spin neuron identity and suppresses D2 type neuron development, and may also play a role in the formation of cardiac pacemaker cells. All in all, Zfp503 is linked to a spectrum of neurological disorders, making it a candidate for therapeutic intervention in these conditions.

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Recombinant Mouse Zinc finger protein 503 (Znf503)