Recombinant Rhesus Macaque Interleukin-8 protein(CXCL8) (Active)

In Stock
Code CSB-AP003171MOW
Product Type Chemokine
Size US$134Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P67813
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias IL-8, Chemokine C-X-C motif, ligand 8
Species Macaca mulatta (Rhesus macaque)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 0.5-5.0 ng/ml.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence AVLPRSAKEL RCECIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE PWVQRVVEKF VKRAENQNP
Research Area Immunology
Source E.coli
Gene Names CXCL8
Expression Region 23-101aa
Tag Info Tag-Free
Mol. Weight 9.14 kDa
Protein Description Full Length of Mature Protein
PubMed ID 7561102; 7628861
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Function IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity).
Subcellular Location Secreted
Protein Families Intercrine alpha (chemokine CxC) family
Database Links

KEGG: mcc:613028

STRING: 9544.ENSMMUP00000005115

UniGene: Mmu.3363

Pathway Chemokine signaling pathway
NF-kappa B signaling pathway
Cellular senescence
IL-17 signaling pathway
NOD-like receptor signaling pathway
Toll-like receptor signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Oxidative Phosphorylation
Phospholipase D signaling pathway

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