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| Code | CSB-AP001791HU |
| Product Type | Interleukin |
| Size |
US$112Purchase it in Cusabio online store (Shop online in the US. Customers outside the US, please order from local distributors.) |
| Uniprot No. | P22301 |
| Lead Time | 5-10 business days |
| Image | |
| Storage Buffer | 0.2 μm filtered PBS, pH 7.4 ,lyophilized |
| Alias | IL-10, CSIF |
| Species | Homo sapiens (Human) |
| Biological_Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine MC/9-2 cells is less than 1 ng/ml, corresponding to a specific activity of >1.0x106 IU/mg. |
| Purity | >95% as determined by SDS-PAGE and HPLC. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | SPGQGTQSEN SCTHFPGNLP NMLRDLRDAF SRVKTFFQMK DQLDNLLLKE SLLEDFKGYL GCQALSEMIQ FYLEEVMPQA ENQDPDIKAH VNSLGENLKT LRLRLRRCHR FLPCENKSKA VEQVKNAFNK LQEKGIYKAM SEFDIFINYI EAYMTMKIRN |
| Research Area | Immunology |
| Source | E.coli |
| Gene Names | IL10 |
| Expression Region | 19-178aa |
| Tag Info | Tag-Free |
| Mol. Weight | 18.6 kDa |
| Protein Description | Full Length of Mature Protein |
| PubMed ID | 1847510; 9405662; 15340161; 8364028; 14657427; 7547951; 8590020; 8897595; 11485736; 15837194; 12825869 |
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| Function | Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. |
| Subcellular Location | Secreted |
| Protein Families | IL-10 family |
| Tissue Specificity | Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types. |
| Database Links |
HGNC: 5962 OMIM: 124092 KEGG: hsa:3586 STRING: 9606.ENSP00000412237 UniGene: Hs.193717 |
| Pathway |
Jak-STAT signaling pathway
T cell receptor signaling pathway FoxO signaling pathway |
IL10 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-RA011580A0HU | IL10 Antibody | Human | ELISA |
IL10 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA011580KA01HU | IL10 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA004870 | IL10 Antibody | Human | WB,ELISA |
IL10 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP011580HU CSB-EP011580HU CSB-BP011580HU CSB-MP011580HU |
Recombinant Human Interleukin-10(IL10) | Yeast E.coli Baculovirus Mammalian cell |
| CSB-RP065944h | Recombinant Human Interleukin-10(IL10) | E.coli |
IL10 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E04593h | Human Interleukin 10,IL-10 ELISA KIT | serum, urine, cell culture supernates, ascitic fluid, cerebrospinal fluid (CSF), saliva | 3.12 pg/mL |
Recombinant Rabbit Integrin beta-8(ITGB8),partial,Yeast
Express system: Yeast
Species: Oryctolagus cuniculus (Rabbit)
Recombinant Human Antigen KI-67(MKI67) ,partial
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human 5-formyltetrahydrofolate cyclo-ligase(MTHFS)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Cytochrome c-type heme lyase(HCCS)
Express system: E.coli
Species: Homo sapiens (Human)
