Recombinant Human B-lymphocyte antigen CD19(CD19),partial

Code CSB-MP004888HU
Product Type Recombinant Protein
Uniprot No. P15391
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Purity Greater than 85% as determined by SDS-PAGE.
Research Area Immunology
Source Mammalian cell
Gene Names CD19
Protein Names Recommended name: B-lymphocyte antigen CD19 Alternative name(s): B-lymphocyte surface antigen B4 Differentiation antigen CD19 T-cell surface antigen Leu-12 CD_antigen= CD19
Expression Region 20-291aa
Tag Info N-terminal 10xHis-tagged and C-terminal Myc-tagged
Mol. Weight 35.1
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Involvement in disease Immunodeficiency, common variable, 3 (CVID3)
Subcellular Location Membrane, Single-pass type I membrane protein
Database Links

HGNC: 1633

OMIM: 107265

KEGG: hsa:930

STRING: 9606.ENSP00000437940

UniGene: Hs.652262

Pathway PI3K-Akt signaling pathway
B cell receptor signaling pathway
Hematopoietic cell lineage

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