Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity.
The following ACD reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ACD Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA839289LA01HU | ACD Antibody |
Human, Mouse | ELISA, WB |
CSB-PA839289LC01HU | ACD Antibody, FITC conjugated |
Human |
ACD Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP677933RA CSB-EP677933RA CSB-BP677933RA CSB-MP677933RA CSB-EP677933RA-B |
Recombinant Rat Adrenocortical dysplasia protein homolog (Acd) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACD Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP682726MO CSB-EP682726MO CSB-BP682726MO CSB-MP682726MO CSB-EP682726MO-B |
Recombinant Mouse Adrenocortical dysplasia protein (Acd) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACD Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP839289HU CSB-EP839289HU CSB-BP839289HU CSB-MP839289HU CSB-EP839289HU-B |
Recombinant Human Adrenocortical dysplasia protein homolog (ACD) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |