ARIH2

ARIH2, also known as Ariadne RBR E3 ubiquitin protein ligase 2, is an essential E3 ubiquitin ligase. It is also commonly referred to as HHARI2. This protein plays a crucial role in the ubiquitination process, tagging proteins for degradation or altering their functions. It is involved in the ubiquitin - proteasome pathway, regulating protein homeostasis.
Dysregulation of ARIH2 has been linked to several diseases, including certain types of cancers. In the field of drug development, researchers are exploring inhibitors that target ARIH2 to disrupt its abnormal activity, with the hope of providing new therapeutic strategies for related diseases.

Popular Product:

ARIH2 Antibody (CSB-PA002069LA01HU)

Validated Data

Western Blot
Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate, Jurkat whole cell lysate, Mouse heart tissue, Mouse liver tissue, Mouse brain tissue
All lanes: ARIH2 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 58 kDa
Observed band size: 58 kDa

Immunohistochemistry of paraffin-embedded human lymph node tissue using CSB-PA002069LA01HU at dilution of 1:100

Western Blot
Positive WB detected in: 293 whole cell lysate, Hela whole cell lysate, 293T whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, U251 whole cell lysate, PC-3 whole cell lysate, Mouse kidney tissue, Mouse brain tissue
All lanes: ARIH2 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 58 kDa
Observed band size: 68 kDa

The following ARIH2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ARIH2 Antibodies

ARIH2 Proteins

ARIH2 Antibodies

ARIH2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA002069GA01HU	ARIH2 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA240267	ARIH2 Antibody	Human,Mouse	ELISA,WB
CSB-PA002069ESR1HU	ARIH2 Antibody	Human	ELISA, IHC
CSB-PA002069LA01HU	ARIH2 Antibody	Human, Mouse	ELISA, WB, IHC

ARIH2 Proteins

ARIH2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP002069HU CSB-EP002069HU CSB-BP002069HU CSB-MP002069HU CSB-EP002069HU-B	Recombinant Human E3 ubiquitin-protein ligase ARIH2 (ARIH2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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