ATG2A encodes Autophagy-related protein 2A. It also goes by some aliases. This protein is pivotal in autophagosome formation, a key process in autophagy. It interacts with other autophagy - related proteins to expand the phagophore membrane.
Regarding signaling pathways, ATG2A is involved in the mTOR pathway, which regulates autophagy. Mutations in ATG2A are associated with certain neurodegenerative diseases, such as amyotrophic lateral sclerosis. Currently, drug research for ATG2A aims to modulate autophagy for treating these related diseases, but it is still in early stages.
Recombinant Human Autophagy-related protein 2 homolog A (ATG2A), partial (CSB-EP648779HU2)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
The following ATG2A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ATG2A Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Code | Product Name | Source |
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CSB-YP600181XBF CSB-EP600181XBF CSB-BP600181XBF CSB-MP600181XBF CSB-EP600181XBF-B |
Recombinant Xenopus tropicalis Autophagy-related protein 2 homolog A (atg2a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG2A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP648779HU CSB-EP648779HU CSB-BP648779HU CSB-MP648779HU CSB-EP648779HU-B |
Recombinant Human Autophagy-related protein 2 homolog A (ATG2A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP648779HU2 | Recombinant Human Autophagy-related protein 2 homolog A (ATG2A), partial | E.coli |
ATG2A Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP744049MO CSB-EP744049MO CSB-BP744049MO CSB-MP744049MO CSB-EP744049MO-B |
Recombinant Mouse Autophagy-related protein 2 homolog A (Atg2a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |