Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
The following BCOR reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
BCOR Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA002635GA01HU | BCOR Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA920864 | BCOR Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA000988 | BCOR Antibody | Human,Mouse | WB, IHC, ELISA |
CSB-PA186525 | BCOR Antibody | Human,Mouse | ELISA,WB |
CSB-PA259179 | BCOR Antibody | Human,Mouse | ELISA,IHC |
CSB-PA761519LA01HU | BCOR Antibody | Human | ELISA |
BCOR Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP761519HU CSB-EP761519HU CSB-BP761519HU CSB-MP761519HU CSB-EP761519HU-B |
Recombinant Human BCL-6 corepressor (BCOR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BCOR Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP807023MO CSB-EP807023MO CSB-BP807023MO CSB-MP807023MO CSB-EP807023MO-B |
Recombinant Mouse BCL-6 corepressor (Bcor), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |