BRCA1

Breast cancer type 1 susceptibility protein is a protein in humans that is encoded by BRCA1 gene. E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation.

BRCA1 Antibodies

BRCA1 Antibodies for Homo sapiens (Human)

BRCA1 Proteins

BRCA1 Proteins for Homo sapiens (Human)

BRCA1 Proteins for Mus musculus (Mouse)

BRCA1 Proteins for Rattus norvegicus (Rat)

BRCA1 Proteins for Macaca mulatta (Rhesus macaque)

BRCA1 Proteins for Pongo pygmaeus (Bornean orangutan)

BRCA1 Proteins for Gorilla gorilla gorilla (Western lowland gorilla)

BRCA1 Proteins for Bos taurus (Bovine)

BRCA1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

BRCA1 Proteins for Pan troglodytes (Chimpanzee)

BRCA1 ELISA Kit

BRCA1 ELISA Kit for Homo sapiens (Human)

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