CACNG1

The protein encoded by CACNG1 is the voltage-dependent calcium channel gamma-1 subunit (Ca_vγ1), also known as Gamma-1 or CACNG1. As an auxiliary subunit of voltage-gated calcium channels (VGCCs), it regulates channel biogenesis, membrane localization, and electrophysiological properties—such as enhancing current amplitude and modifying inactivation kinetics—to control calcium influx and downstream signaling pathways.
Dysfunction of CACNG1 is associated with neurological disorders like epilepsy and neuropathic pain, where aberrant calcium signaling disrupts neuronal excitability. Preclinical studies are exploring small-molecule modulators targeting Ca_vγ1 as potential therapies, aiming to restore normal VGCC function and alleviate symptoms of these conditions.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The following CACNG1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CACNG1 Antibodies

CACNG1 Proteins

CACNG1 Antibodies

CACNG1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA060130	CACNG1 Antibody	Human,Mouse,Rat	WB, ELISA

CACNG1 Proteins

CACNG1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF004415HU	Recombinant Human Voltage-dependent calcium channel gamma-1 subunit (CACNG1)	in vitro E.coli expression system
CSB-YP004415HU1 CSB-BP004415HU1 CSB-MP004415HU1 CSB-EP004415HU1-B	Recombinant Human Voltage-dependent calcium channel gamma-1 subunit (CACNG1), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP004415HU1	Recombinant Human Voltage-dependent calcium channel gamma-1 subunit (CACNG1), partial	E.coli

CACNG1 Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-CF004415RB	Recombinant Rabbit Voltage-dependent calcium channel gamma-1 subunit (CACNG1)	in vitro E.coli expression system
CSB-YP004415RB1 CSB-EP004415RB1 CSB-BP004415RB1 CSB-MP004415RB1 CSB-EP004415RB1-B	Recombinant Rabbit Voltage-dependent calcium channel gamma-1 subunit (CACNG1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CACNG1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-CF600944BO	Recombinant Bovine Voltage-dependent calcium channel gamma-1 subunit (CACNG1)	in vitro E.coli expression system
CSB-YP600944BO1 CSB-EP600944BO1 CSB-BP600944BO1 CSB-MP600944BO1 CSB-EP600944BO1-B	Recombinant Bovine Voltage-dependent calcium channel gamma-1 subunit (CACNG1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CACNG1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF004415MO	Recombinant Mouse Voltage-dependent calcium channel gamma-1 subunit (Cacng1)	in vitro E.coli expression system
CSB-YP004415MO1 CSB-EP004415MO1 CSB-BP004415MO1 CSB-MP004415MO1 CSB-EP004415MO1-B	Recombinant Mouse Voltage-dependent calcium channel gamma-1 subunit (Cacng1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CACNG1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-CF004415RA	Recombinant Rat Voltage-dependent calcium channel gamma-1 subunit (Cacng1)	in vitro E.coli expression system
CSB-YP004415RA1 CSB-EP004415RA1 CSB-BP004415RA1 CSB-MP004415RA1 CSB-EP004415RA1-B	Recombinant Rat Voltage-dependent calcium channel gamma-1 subunit (Cacng1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CACNG1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-CF644833PI	Recombinant Pig Voltage-dependent calcium channel gamma-1 subunit (CACNG1)	in vitro E.coli expression system
CSB-YP644833PI1 CSB-EP644833PI1 CSB-BP644833PI1 CSB-MP644833PI1 CSB-EP644833PI1-B	Recombinant Pig Voltage-dependent calcium channel gamma-1 subunit (CACNG1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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CACNG1

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