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Calcium/calmodulin-dependent protein kinase kinase 2 is a protein in humans that is encoded by CAMKK2 gene. Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity).
The following CAMKK2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CAMKK2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA004473GA01HU | CAMKK2 Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA582406 | CAMKK2 Antibody |
Human | ELISA,WB,IHC |
| CSB-PA006677 | CAMKK2 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA822299LA01HU | CAMKK2 Antibody |
Human | ELISA, IHC |
| CSB-PA822299LB01HU | CAMKK2 Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA822299LC01HU | CAMKK2 Antibody, FITC conjugated |
Human | |
| CSB-PA822299LD01HU | CAMKK2 Antibody, Biotin conjugated |
Human | ELISA |
CAMKK2 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004473RA CSB-EP004473RA CSB-BP004473RA CSB-MP004473RA CSB-EP004473RA-B |
Recombinant Rat Calcium/calmodulin-dependent protein kinase kinase 2 (Camkk2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CAMKK2 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP805375MO CSB-EP805375MO CSB-BP805375MO CSB-MP805375MO CSB-EP805375MO-B |
Recombinant Mouse Calcium/calmodulin-dependent protein kinase kinase 2 (Camkk2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CAMKK2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP822299HU CSB-EP822299HU CSB-BP822299HU CSB-MP822299HU CSB-EP822299HU-B |
Recombinant Human Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Calcium/calmodulin-dependent protein kinase kinase 2 is a protein in humans that is encoded by the CAMKK2 gene. The CAMKK2 is a calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in many cellular processes. CAMKK2 isoform 1, isoform 2, and isoform 3 can phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1, and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). It seems to be involved in hippocampal activation of CREB1 (By similarity).
