The following CAMKK2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CAMKK2 Antibodies

CAMKK2 Antibodies for Homo sapiens (Human)

CAMKK2 Proteins

CAMKK2 Proteins for Rattus norvegicus (Rat)

CAMKK2 Proteins for Mus musculus (Mouse)

CAMKK2 Proteins for Homo sapiens (Human)

CAMKK2 Background

Calcium/calmodulin-dependent protein kinase kinase 2 is a protein in humans that is encoded by the CAMKK2 gene. The CAMKK2 is a calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in many cellular processes. CAMKK2 isoform 1, isoform 2, and isoform 3 can phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1, and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). It seems to be involved in hippocampal activation of CREB1 (By similarity).

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