CHMP6 Research Reagents

Charged multivesicular body protein 6 is a protein in humans that is encoded by CHMP6 gene. Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).

The following CHMP6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CHMP6 Antibodies

CHMP6 Antibodies for Homo sapiens (Human)

CHMP6 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

CHMP6 Proteins

CHMP6 Proteins for Mus musculus (Mouse)

CHMP6 Proteins for Dictyostelium discoideum (Slime mold)

CHMP6 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

CHMP6 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

CHMP6 Proteins for Gallus gallus (Chicken)

CHMP6 Proteins for Homo sapiens (Human)

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