CLEC6A encodes the C-type lectin domain containing 6A protein, also known as Dectin-2. Dectin-2 is a pattern - recognition receptor mainly expressed on myeloid cells. It recognizes carbohydrate structures on pathogens, triggering intracellular signaling cascades. This protein is involved in the Syk - CARD9 - NF - κB pathway, which is crucial for innate immune responses.
Dysregulation of CLEC6A has been linked to various infectious diseases and autoimmune disorders. Scientists are exploring drugs that target CLEC6A to modulate immune responses. Some small - molecule inhibitors are in pre - clinical studies, aiming to treat diseases related to abnormal immune activation.
CLEC4A Antibody (CSB-PA412681)
Validated Data
Western Blot analysis of HEPG2 cells using CLECSF6 Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
The following CLEC6A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CLEC6A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA181586 | CLEC4A Antibody | Human,Mouse | ELISA,WB |
CSB-PA016840 | CLEC4A Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA412681 | CLEC4A Antibody | Human | WB,ELISA |
CLEC6A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP891558HU CSB-EP891558HU CSB-BP891558HU CSB-MP891558HU CSB-EP891558HU-B |
Recombinant Human C-type lectin domain family 4 member A (CLEC4A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |