CRAMP1

CRAMP1, also known as Cathelicidin-Related Antimicrobial Peptide 1, is a crucial protein with multiple aliases. It plays vital roles in the innate immune system. The peptide exerts its antibacterial effects by disrupting the bacterial cell membrane, a well - known mechanism of action. It is involved in the Toll - like receptor signaling pathway, which is essential for immune response initiation.
In terms of diseases, abnormal expression of CRAMP1 is associated with certain infectious and inflammatory disorders. Currently, in drug development, CRAMP1 - derived peptides are being explored as potential antibiotics, aiming to address the issue of antibiotic resistance. Such research shows great promise for future therapeutic applications.