CSF1R

The Csf1r gene encodes the Colony Stimulating Factor 1 Receptor. Common aliases include CD115 and CSF-1R. It is a receptor tyrosine kinase. The binding of its ligand, CSF-1 or IL-34, triggers autophosphorylation of the receptor, activating multiple signaling pathways such as the PI3K/Akt and Ras/Raf/MEK/ERK pathways.
CSF1R is involved in the regulation of monocyte, macrophage, and osteoclast development. Dysregulation of CSF1R is associated with various diseases, including certain cancers, autoimmune diseases, and neurodegenerative disorders. Currently, CSF1R inhibitors are being actively developed for cancer immunotherapy, aiming to modulate the tumor microenvironment and enhance anti - tumor immunity.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSF1R Antibody (CSB-PA007334)

Validated Data

Western Blot analysis of COLO cells using c-Fms Polyclonal Antibody

Western Blot analysis of HEPG2 using c-Fms Polyclonal Antibody

Human Macrophage Colony-Stimulating Factor Receptor,M-CSFR ELISA Kit (CSB-E10012h)

Validated Data

Code: CSB-E10012h

Size: 96T,5×96T,10×96T

Sensitivity: 0.039 ng/mL

Detection Range: 0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following CSF1R reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CSF1R Antibodies

CSF1R Proteins

CSF1R ELISA Kits

CSF1R Antibodies

CSF1R Antibodies for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Species Reactivity	Application
CSB-PA006044LA01CA	CSF1R Antibody	Felis silvestris catus	ELISA

CSF1R Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA084386	Phospho-CSF1R (Tyr809) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA924224	Phospho-CSF1R (Tyr561) Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA202220	Phospho-CSF1R (Tyr708) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA696464	CSF1R (Ab-809) Antibody	Human,Mouse	ELISA,WB,IHC,IF
CSB-PA152912	Phospho-CSF1R (Tyr699) Antibody	Human	ELISA,WB
CSB-PA940519	Phospho-CSF1R (Tyr809) Antibody	Human	ELISA,IHC
CSB-PA001596	CSF1R Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA001597	CSF1R Antibody	Human	WB, IHC, IF, ELISA
CSB-PA007328	Phospho-CSF1R (Y809) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA007329	Phospho-CSF1R (Y699) Antibody	Human	WB, ELISA
CSB-PA007330	Phospho-CSF1R (Y708) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA007331	Phospho-CSF1R (Y723) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA007332	Phospho-CSF1R (Y561) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA007333	Phospho-CSF1R (Y809) Antibody	Human	IHC, ELISA
CSB-PA007334	CSF1R Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA007335	CSF1R Antibody	Human	WB, ELISA
CSB-PA007337	CSF1R Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA300271	CSF1R Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA678661	CSF1R Antibody	Human,Mouse,Rat	ELISA,WB

CSF1R Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA888246XA01DIL	csf1r Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

CSF1R Proteins

CSF1R Proteins for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Source
CSB-YP006044CA CSB-BP006044CA CSB-MP006044CA CSB-EP006044CA-B	Recombinant Cat Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006044CA	Recombinant Cat Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	E.coli

CSF1R Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP006044HU CSB-EP006044HU CSB-BP006044HU CSB-MP006044HU CSB-EP006044HU-B	Recombinant Human Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-MP006044HU	Recombinant Human Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	Mammalian cell
CSB-MP006044HUi10	Recombinant Human Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	Mammalian cell
CSB-MP006044HUd7	Recombinant Human Macrophage colony-stimulating factor 1 receptor (CSF1R), partial (Active)	Mammalian cell

CSF1R Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP006044MO CSB-EP006044MO CSB-BP006044MO CSB-EP006044MO-B	Recombinant Mouse Macrophage colony-stimulating factor 1 receptor (Csf1r), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli

CSF1R Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP888246DIL CSB-EP888246DIL CSB-BP888246DIL CSB-MP888246DIL CSB-EP888246DIL-B	Recombinant Danio rerio Macrophage colony-stimulating factor 1 receptor (csf1r), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CSF1R ELISA Kit

CSF1R ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E10012h	Human Macrophage Colony-Stimulating Factor Receptor,M-CSFR ELISA Kit	serum, plasma, tissue homogenates	0.039 ng/mL

CSF1R ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-EL006044RA	Rat Macrophage colony-stimulating factor 1 receptor(CSF1R) ELISA kit	serum, plasma, tissue homogenates	0.078 ng/mL

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CSF1R

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