The protein encoded by CUTA (CutA divalent cation tolerance homolog) is commonly referred to as CutA1. It regulates divalent cation homeostasis by modulating the transport or sequestration of metal ions like copper, zinc, and calcium, which is essential for maintaining enzyme activity and membrane integrity in cells.
Dysregulated CUTA expression has been associated with neurodegenerative disorders, where abnormal metal ion accumulation contributes to neuronal damage. Preclinical studies are exploring its role in disease pathogenesis, aiming to develop interventions that restore cation balance, though targeted drugs are still in early research stages.
CUTA Antibody (CSB-PA006226LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA006226LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA006226LA01HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA006226LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following CUTA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CUTA Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA006226LA01HU | CUTA Antibody | Human | ELISA, IHC, IF |
| CSB-PA006226LD01HU | CUTA Antibody, Biotin conjugated | Human | ELISA |
CUTA Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP006226HU CSB-EP006226HU CSB-BP006226HU CSB-MP006226HU CSB-EP006226HU-B |
Recombinant Human Protein CutA (CUTA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |